Dietary supplement affects lung tumor growth differently in male and female mice

A new study from UCLA Health Jonsson Comprehensive Cancer Center suggests that a dietary supplement containing calcium alpha-ketoglutarate (Ca-αKG) may impact lung tumor development differently depending on the sex of the test subject.

Researchers observed that female mice given the supplement experienced slower tumor growth and activation of genes linked to improved cancer outcomes in women. These findings highlight a potential gender-specific response to the molecule.

In contrast, male mice treated with the same supplement showed accelerated tumor growth and increased cell proliferation, raising questions about its safety and efficacy in different sexes.

The study underscores the need for further research to explore how such supplements might interact with human biology and whether similar gender-based differences exist in people.

Based on reporting from Medical Xpress (Cancer).

Source: Medical Xpress (Cancer). This article was drafted by AI from that reporting and reviewed by an automated accuracy check before publishing.